Könyv Adenosinergic and autophagic mechanisms in Huntington's diseases Anil Kumar

Adenosinergic and autophagic mechanisms in Huntington's diseases

Nyelv: Angol
Kötés: Puha kötésű
Elérhetőség: Beszállítói készleten
Küldés 5-8 napon belül
22 299 Ft
Huntington disease is a complex neurodegenerative disorder. Presently, it is being treated sympatoma...

Információk a könyvről

Nyelv
Angol
Kötés
Könyv - Puha kötésű
Kiadva
2016
oldal
180
EAN
9783659916830
Enbook ID
13728411
Súly
284
Méretek
150 x 220 x 11

Teljes leírás

Huntington disease is a complex neurodegenerative disorder. Presently, it is being treated sympatomatically based on patient symptoms/ condition. Present work is an attempt of authors to share their observation that treatment with caffeine and dipyridamole displayed significant protection highlighting their neuroprotective efficacy in HD like conditions.This further confirmed that targeting adenosinergic system could be an important therapeutic strategy in the management of HD like symptoms. Further, it has been observed that treatment with rapamycin caused marked improvement in the QA induced behavioural (motor and memory) alteration, oxidative burden, mitochondrial dysfunction, neuroinflammation, apoptosis, neurotrophin levels highlighting role of autophagy in excitotoxic conditions.

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