Alterations in Mammary Epithelial Cell Identity

Name: Alterations in Mammary Epithelial Cell Identity
Brand: Edizioni Accademiche Italiane
SKU: 9783639656244
Price: 15713 HUF
Availability: InStock

Potential Tools for Breast Cancer Risk Assessment and Prevention

Szerző: Danila Coradini, Saro Oriana

Nyelv:

Kötés: Puha kötésű

Kiadó: Edizioni Accademiche Italiane

Elérhetőség: Beszállítói készleten

Küldés 8-11 napon belül

15 713 Ft

In the next future, cancer prevention will be the main concern. Therefore, elucidating the molecular...

Információk a könyvről

Szerző

Danila Coradini, Saro Oriana

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2014

oldal

112

EAN

9783639656244

ISBN

3639656245

Enbook ID

07175417

Kiadó

Edizioni Accademiche Italiane

Súly

177

Méretek

152 x 229 x 7

Teljes leírás

In the next future, cancer prevention will be the main concern. Therefore, elucidating the molecular mechanisms that, if altered, may trigger the neoplastic transformation of the cells that form human mammary gland, is crucial to prevent breast cancer, the leading cause of cancer death in women. Growing evidences indicate that the epigenetic control of gene expression plays a key role in the homeostasis of the mammary tissue, and suggest that alterations in this control can affect the identity of the epithelial cells and trigger their transformation. Since, unlike genetic alterations, epigenetic changes are potentially reversible, a better understanding of the mechanisms that regulate the establishment and maintenance of cell identity can provide valuable information to develop innovative strategies for cancer prevention aimed at reverting epigenome dysfunctions and hindering tumorigenesis. In this book, after describing the biological basis of cell identity establishment and maintenance, the authors discuss the effects of cell identity disruption in two different benign lesions and propose some interesting epigenome-targeting strategies potentially useful for cancer prevention.

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Alterations in Mammary Epithelial Cell Identity

Potential Tools for Breast Cancer Risk Assessment and Prevention

Információk a könyvről

Teljes leírás

Érdekelheti

Azok a vásárlók, akik ezt a könyvet megvásárolták, a következőket is megvásárolták