Analytical Method Development and Validation

Name: Analytical Method Development and Validation
Brand: LAP Lambert Academic Publishing
SKU: 9783659253997
Price: 64608 HUF
Availability: InStock

Simultaneous Estimation of Pioglitazone and Glimepiride in Tablet Dosage Form by RP-HPLC

Szerző: Gagan Sharma, Ravi Sharma

Nyelv:

Kötés: Puha kötésű

Kiadó: LAP Lambert Academic Publishing

Elérhetőség: Beszállítói készleten

Küldés 5-8 napon belül

64 608 Ft

A simple reverse phase liquid Chromatographic method has been developed and subsequently validated f...

Információk a könyvről

Szerző

Gagan Sharma, Ravi Sharma

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2012

oldal

112

EAN

9783659253997

Enbook ID

07089537

Kiadó

LAP Lambert Academic Publishing

Súly

183

Méretek

150 x 220 x 7

Teljes leírás

A simple reverse phase liquid Chromatographic method has been developed and subsequently validated for simultaneous determination of Pioglitazone and Glimepiride in combination. The separation was carried out using a mobile phase of phosphate buffer (pH-4.5): Acetonitrile (45:55) v/v and using methanol as diluent. The column used was Inertsil ODS (250 mm x 4.6 mm i.d., 5 m) with flow rate of 1 ml/min using UV detection at 225 nm. The described method was linear over a concentration range of 5-50 g/ml and 5-25 g/ml for the assay of Pioglitazone and Glimepiride respectively. The retention times of Pioglitazone and Glimepiride were found to be4.6 and 7.7min respectively. Results of analysis were validated statistically and by recovery studies. The results of the study showed that the proposed RP-HPLC method is simple, rapid, precise and accurate, which is useful for the routine determination of Pioglitazone and Glimepiride bulk drug and in its pharmaceutical dosage form.

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Analytical Method Development and Validation

Simultaneous Estimation of Pioglitazone and Glimepiride in Tablet Dosage Form by RP-HPLC

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Teljes leírás

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Azok a vásárlók, akik ezt a könyvet megvásárolták, a következőket is megvásárolták