The book presents a thorough and comprehensive exploration of the integration of AI into chemistry. It covers foundational concepts, practical applications, and advanced techniques, providing a step-by-step approach to mastering these skills. Importantly, the inclusion of detailed tutorials, practical exercises, and real-world case studies significantly benefits readers by providing practical insights and skills. In addition, the companion website and specialized large language model for ongoing support is a forward-thinking addition that adds considerable value to the readers. This book serves as a comprehensive tutorial for traditional chemists, guiding them through the integration of AI, automation, data science, and cheminformatics into their research.