Atomic Force Microscope and Cell Biology

Name: Atomic Force Microscope and Cell Biology
Brand: VDM Verlag Dr. Müller
SKU: 9783639187205
Price: 17195 HUF
Availability: InStock

The mechanical properties from the membrane to the interior of the cell

Szerző: Charles Roduit

Nyelv:

Kötés: Puha kötésű

Kiadó: VDM Verlag Dr. Müller

Elérhetőség: Kiadói készleten rendelésre

Küldés 17-27 napon belül

17 195 Ft

This book describes the doctoral thesis where we explore the mechanical properties of living cells u...

Információk a könyvről

Szerző

Charles Roduit

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2009

oldal

120

EAN

9783639187205

Enbook ID

06826861

Kiadó

VDM Verlag Dr. Müller

Súly

215

Méretek

152 x 220 x 13

Teljes leírás

This book describes the doctoral thesis where we explore the mechanical properties of living cells using the Atomic Force Microscope (AFM). The cell membrane contains lipids microdomains, called rafts, enriched in cholesterol and sphingolipids. The lipid rafts are believed to play an important role in signal processing by acting as a signaling platform . The mechanical properties of these rafts were characterized by targeting one of its component, the GPI-anchored protein. This work revealed these domains to be stiffer than the surrounding membrane. The stiffness specificity of rafts may be related to the lower diffusion rate of proteins and can be, therefore, an important property for its role as a signaling platform. During this thesis, we also introduced a new AFM imaging mode, which we called stiffness tomography . With this imaging mode, we were able to distinguish stiff materials inclusion located into the sample. A significant part of this project was the development of a post-processing software to automate the computations of the acquired data. In this book we describes the algorithms used in the open-source version of this software.

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Atomic Force Microscope and Cell Biology

The mechanical properties from the membrane to the interior of the cell

Információk a könyvről

Teljes leírás

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Azok a vásárlók, akik ezt a könyvet megvásárolták, a következőket is megvásárolták