Cardiovascular Proteomics

Name: Cardiovascular Proteomics
Brand: Humana Press Inc.
SKU: 9781588295354
Price: 38542 HUF
Availability: InStock

Methods and Protocols

Szerző: Fernando Vivanco

Nyelv:

Kötés: Kemény kötésű

Kiadó: Humana Press Inc.

Elérhetőség: Beszállítói készleten

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This cutting-edge book presents protocols and strategies for proteomic evaluation of cardiovascular...

Információk a könyvről

Szerző

Fernando Vivanco

Nyelv

Angol

Kötés

Könyv - Kemény kötésű

Kiadva

2007

oldal

432

EAN

9781588295354

ISBN

1588295354

Enbook ID

01430485

Kiadó

Humana Press Inc.

Súly

903

Méretek

155 x 235 x 31

Teljes leírás

This cutting-edge book presents protocols and strategies for proteomic evaluation of cardiovascular disease written by pioneering researchers in the field. Topics explored in this comprehensive volume include obtaining specific heart proteins, techniques for identifying risk biomarkers of atherome plaque rupture, analyzing the secretome of explanted endarterectomies cultured in vitro, and phage display techniques for deciphering the molecular diversity of blood vessels.Cardiovascular Proteomics: Methods and Protocols presents cutting-edge protocols and strategies for proteomic evaluation of cardiovascular disease written by pioneering researchers in the field. Topics explored in this comprehensive volume include obtaining specific heart proteins, cutting-edge techniques for identifying risk biomarkers of atherome plaque rupture, analyzing the secretome of explanted endarterectomies cultured in vitro, and phage display techniques for deciphering the molecular diversity of blood vessels. Detailed protocols for the isolation of short- and long-term culture of the adult mouse cardiac myocytes are also included.§Numerous advanced proteomic techniques are addressed, including protein separation by two-dimensional electrophoresis and two-dimensional difference gel electrophoresis, liquid chromatography coupled to mass spectrometry, and the SELDI-TOF approach to searching for biomarkers of stroke in human serum or of hypertension in the serum of animal models. Proteomic strategies and protocols for studying the proteome of endothelial, arterial smooth muscle cells, foam cells, and circulating blood monocytes constitute a major element of this text. Cutting-edge techniques for the analysis of subproteomes from isolation to final characterization and the characterization of posttranslational modifications are also addressed. This useful snapshot of current proteomic techniques is a single source for protocols for the identification and validation of novel biomarkers and targets in cardiovascular diseases.

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Cardiovascular Proteomics

Methods and Protocols

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Teljes leírás

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