Complement Methods and Protocols

Name: Complement Methods and Protocols
Brand: Humana Press Inc.
SKU: 9780896036543
Price: 63724 HUF
Availability: InStock

Szerző: B. Paul Morgan

Nyelv:

Kötés: Kemény kötésű

Kiadó: Humana Press Inc.

Elérhetőség: Beszállítói készleten alacsony példányszámban

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The complement system, first described more than a century ago, was for many years the ugly duckling...

Információk a könyvről

Szerző

B. Paul Morgan

Nyelv

Angol

Kötés

Könyv - Kemény kötésű

Kiadva

2000

oldal

259

EAN

9780896036543

ISBN

0896036545

Enbook ID

02716585

Kiadó

Humana Press Inc.

Súly

584

Méretek

241 x 165 x 22

Teljes leírás

The complement system, first described more than a century ago, was for many years the ugly duckling of the immunology world, but no more. Complement in recent years has blossomed into a fascinating and fast moving field of immediate relevance to clinical scientists in fields as diverse as transplantation biology, virology, and inflammation. Despite its emergence from the shadows, complement retains an unwarranted reputation for being difficult. This impression derives in large part from the superficially complicated nomenclature, a relic of the long and tortuous process of unraveling the system, of naming components in order of discovery rather than in a syst- atic manner. Once the barrier of nomenclature has been surmounted, then the true simplicity of the system becomes apparent. Complement comprises an activation system and a cytolytic system. The former has diverged to focus on complement to distinct targets bacteria, - mune complexes, and others so that texts now describe three activation pa- ways, closely related to one another, but each with some unique features. The cytolytic pathway is the same regardless of the activation process and kills cells by creating pores in the membrane. Complement plays an important role in killing bacteria and is essential for the proper handling of immune complexes. Problems occur when complement is activated in an inappropriate manner the potent inflammation-inducing products of the cascade then cause unwanted tissue damage and destruction.

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Complement Methods and Protocols

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