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Könyv Computational Design of Ligand Binding Proteins BARRY L. STODDARD

Computational Design of Ligand Binding Proteins

Szerző: BARRY L. STODDARD
Nyelv: Angol
Kötés: Puha kötésű
Kiadó: Humana Press Inc.
Elérhetőség: Beszállítói készleten
Küldés 5-8 napon belül
38 967 Ft
This volume provides a collection of protocols and approaches for the creation of novel ligand bindi...

Információk a könyvről

Szerző
BARRY L. STODDARD
Nyelv
Angol
Kötés
Könyv - Puha kötésű
Kiadva
2018
oldal
375
EAN
9781493980802
ISBN
9781493980802
Enbook ID
19700401
Kiadó
Humana Press Inc.
Súly
743
Méretek
178 x 254 x 21

Teljes leírás

This volume provides a collection of protocols and approaches for the creation of novel ligand binding proteins, compiled and described by many of today's leaders in the field of protein engineering. Chapters focus on modeling protein ligand binding sites, accurate modeling of protein-ligand conformational sampling, scoring of individual docked solutions, structure-based design program such as ROSETTA, protein engineering, and additional methodological approaches. Examples of applications include the design of metal-binding proteins and light-induced ligand binding proteins, the creation of binding proteins that also display catalytic activity, and the binding of larger peptide, protein, DNA and RNA ligands. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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