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Könyv Computational Protein Localization Prediction Stefan Maetschke

Computational Protein Localization Prediction

Topological Models of Transmembrane Proteins for Localization Prediction

Szerző: Stefan Maetschke
Nyelv: Angol
Kötés: Puha kötésű
Kiadó: VDM Verlag Dr. Müller
Elérhetőség: Kiadói készleten rendelésre
Küldés 17-27 napon belül
27 978 Ft
Proteins are distributed to the organelles of the§cell by a highly complex sorting machinery. Since§...

Információk a könyvről

Szerző
Stefan Maetschke
Nyelv
Angol
Kötés
Könyv - Puha kötésű
Kiadva
2009
oldal
280
EAN
9783639137415
Enbook ID
06822403
Kiadó
VDM Verlag Dr. Müller
Súly
433
Méretek
150 x 220 x 17

Teljes leírás

Proteins are distributed to the organelles of the§cell by a highly complex sorting machinery. Since§experimental localization techniques are time§consuming and expensive, various computational§techniques to predict the subcellular localization of§proteins have been developed. This book describes the§biological signals and mechanisms that guide protein§localization, and the computational methods employed§for localization prediction. The focus is thereby on§transmembrane proteins, an important class of§proteins that are inserted into the membranes of the§cell. Different topological models of transmembrane§proteins, utilizing Support Vector Machines, Hidden§Markov Models and Conditional Random Fields, are§studied and their prediction performances are§evaluated. The methods described in this book should§be of interest to all researchers working in the§field of protein localization prediction.

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