Könyv Cortical Electrical Stimulation in Epilepsy Surgery Vasileios Kokkinos

Cortical Electrical Stimulation in Epilepsy Surgery

Single-Pulse Electrical Stimulation for Localization of the Epileptogenic Zone

Nyelv: Angol
Kötés: Puha kötésű
Kiadó: VDM Verlag
Elérhetőség: Beszállítói készleten
Küldés 14-21 napon belül
22 890 Ft
Evaluation of neuronal responses to single-pulse electrical stimulation (SPES) was performed to dete...

Információk a könyvről

Nyelv
Angol
Kötés
Könyv - Puha kötésű
Kiadva
2010
oldal
132
EAN
9783639263084
ISBN
3639263081
Enbook ID
06833646
Kiadó
Súly
204
Méretek
152 x 229 x 8

Teljes leírás

Evaluation of neuronal responses to single-pulse electrical stimulation (SPES) was performed to determine the reliability of cortical stimulation under general anaesthesia compared to alert awareness. Nine patients with intractable epilepsy, candidates for epilepsy surgery, underwent SPES during both electrode implantation and telemetry recording. Early, delayed, repeated, fixed and oscillatory neuronal responses to SPES were investigated. Analysis showed that: a) early responses are normal markers of synaptic efficacy, b) delayed responses are markers of epileptogenicity, c) repeated responses are normal variants of deep cortical stimulation, d) fixed responses are markers of normal connectivity underlying sensory processing functions, and e) oscillatory responses are normal markers of pacemaking capability of deep brain structures. This study produced evidence that the main pathological markers have a high correlation between implantation and telemetry SPES procedures. Results render SPES an equally reliable process under both anaesthesia and alert awareness.

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