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Könyv Cytogenetics of Down Syndrome Dian Salih

Cytogenetics of Down Syndrome

Clinical and Cytogenetic profile in patients with Down syndrome in Duhok province Kurdistan region-Iraq

Szerző: Dian Salih
Nyelv: Angol
Kötés: Puha kötésű
Kiadó: Noor Publishing
Elérhetőség: Beszállítói készleten
Küldés 5-8 napon belül
17 180 Ft
Down syndrome is the most common autosomal chromosomal aneuploidy in human and the best known of all...

Információk a könyvről

Szerző
Dian Salih
Nyelv
Angol
Kötés
Könyv - Puha kötésű
Kiadva
2017
oldal
108
EAN
9783330804159
ISBN
3330804157
Enbook ID
16068899
Kiadó
Noor Publishing
Súly
177
Méretek
150 x 220 x 6

Teljes leírás

Down syndrome is the most common autosomal chromosomal aneuploidy in human and the best known of all malformation syndromes associated with developmental delay, mental retardation and several characteristic physical features. The birth prevalence of Down syndrome is approximately 1 in 650-1000 live-born children world-wide which make the syndrome the most common cause of mental retardation. According to the American College of Obstetricians and Gynecologists reports a woman's risk for having a child with Down syndrome is 1 in 1,000 at age of 30, 1 in 400 at age of 35, and 1 in 100 at age of 40. Generally, more than 95% of Down syndrome individuals have trisomy 21 which results from non-disjunction error during gametogenesis in chromosome 21. About 2-4% results from a translocation of chromosome 21, while only 1-2% is mosaicism that showing a normal cell line additionally to trisomy. Mosaic Down syndrome individuals may be phenotypically less severely affected than Individuals in trisomy or translocation, but their conditions are indistinguishable in all other aspects.

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