Könyv Debating Cancer: The Paradox In Cancer Research Henry H. Q. Heng

Debating Cancer: The Paradox In Cancer Research

Szerző: Henry H. Q. Heng
Nyelv: Angol
Kötés: Kemény kötésű
Elérhetőség: Beszállítói készleten
Küldés 10-13 napon belül
59 285 Ft
Cancer research is at a crossroads. Traditionally, cancer has been thought of as a disease of gene m...

Információk a könyvről

Nyelv
Angol
Kötés
Könyv - Kemény kötésű
Kiadva
2015
oldal
464
EAN
9789814520843
ISBN
9814520845
Enbook ID
05071054
Súly
796
Méretek
236 x 164 x 30

Teljes leírás

Cancer research is at a crossroads. Traditionally, cancer has been thought of as a disease of gene mutation, where the stepwise accumulation of cancer gene mutations is the key, and the identification of common gene mutations has been considered to be essential for diagnosis and treatment. Despite extensive research efforts and accumulated knowledge on cancer genes and pathways, the clinical benefits of this traditional approach have been limited. Recently, cancer genome sequencing has revealed an extensive amount of genetic heterogeneity where the long expected common mutation drivers have been difficult, if not impossible, to identify. These realities ultimately challenge the conceptual framework of current cancer biology. This book introduces a new concept of genome theory of cancer evolution to unify the field. Many important and representative, but often confusing, questions and paradoxes will be critically analyzed. By comparing gene and genome-based theories, the hidden flaws of many popular viewpoints are addressed. This discussion is intended to initiate a much-needed critical re-evaluation of current cancer research.

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