Development of Novel Indolyl-derived Biologically Active Compounds

Name: Development of Novel Indolyl-derived Biologically Active Compounds
Brand: LAP Lambert Academic Publishing
SKU: 9783659320712
Price: 27642 HUF
Availability: InStock

Synthesis, Characterization and Applications as (Anti-MRSA, Anticancer)

Szerző: Mardia El Sayed

Nyelv:

Kötés: Puha kötésű

Kiadó: LAP Lambert Academic Publishing

Elérhetőség: Beszállítói készleten

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MRSA is a methicillin-resistance Staphylococcus aureus and a strain of Staphylococcus aureus that de...

Információk a könyvről

Szerző

Mardia El Sayed

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2015

oldal

312

EAN

9783659320712

Enbook ID

09299611

Kiadó

LAP Lambert Academic Publishing

Súly

481

Méretek

150 x 220 x 19

Teljes leírás

MRSA is a methicillin-resistance Staphylococcus aureus and a strain of Staphylococcus aureus that developed resistance to the killing effect of the -lactam antibiotics, which include the penicillins (methicillin, dicloxacillin, oxacillin, etc.), MRSA is sometimes called a "superbug" because it is very difficult to treat and it causes a huge number of infections every year in hospitals all over the world. The novel synthesized indoles will add a valuable new addition to the antibacterial arsenal for MRSA infections, it would be new bactericidal agents effective against resistant isolates or standard. We have shown for the first time that the cycloalkanoindoles,bis-indolobenzocarbazoles and the oxidized bis-indolylmethenes inhibited growth of drug resistant MRSA either standard or isolate and other Gram-positive bacteria at low concentrations. Some of these novel bis- and tris-indolyl compounds described in this work have been screened in the national cancer institute (NCI) in USA for one and five dose that showed the highest antipoliferative activity in a nanomolar scale towards the selected cancers cell lines (Non small lung: NCIeH460, Ovarian: OVCAR-4 and Breast: MCF).

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Development of Novel Indolyl-derived Biologically Active Compounds

Synthesis, Characterization and Applications as (Anti-MRSA, Anticancer)

Információk a könyvről

Teljes leírás

Érdekelheti

Azok a vásárlók, akik ezt a könyvet megvásárolták, a következőket is megvásárolták