DNA Sequence Specific Binding of Some Anticancer Drugs

Name: DNA Sequence Specific Binding of Some Anticancer Drugs
Brand: LAP Lambert Academic Publishing
SKU: 9783659240980
Price: 15317 HUF
Availability: InStock

A Force Field Studies

Szerző: Bipul Bezbaruah, Chitrani Medhi

Nyelv:

Kötés: Puha kötésű

Kiadó: LAP Lambert Academic Publishing

Elérhetőség: Beszállítói készleten

Küldés 5-8 napon belül

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Anticancer drugs are highly sequence specific to the DNA nucleobases, i.e. they bind specifically by...

Információk a könyvről

Szerző

Bipul Bezbaruah, Chitrani Medhi

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2012

oldal

EAN

9783659240980

Enbook ID

06887455

Kiadó

LAP Lambert Academic Publishing

Súly

149

Méretek

150 x 220 x 5

Teljes leírás

Anticancer drugs are highly sequence specific to the DNA nucleobases, i.e. they bind specifically by choosing a selective sequence within DNA nucleobase. The Anticancer Drugs may bind within DNA nucleobase basically by intercalation, groove binding and both intercalation or groove binding. In this book some groove binding and intercalating anticancer drugs are taken to study their sequence specific binding within DNA nucleobase. In the second Chapter , is it trying to investigate the binding mode of Acridine drugs within DNA nucleobase, which is as a good intercalating anticancer drug. Chapter 3 explains the binding mode of some groove binding anticancer drugs, DAPI drugs. Here it is also trying to investigate whether the drug prefers minor or major groove within DNA nucleobase. And in the last chapter, a good anticancer drug, Daunomycin is taken, which may bind two different ways within DNA nucleobases as intercalation and groove binding, here some part of the drug prefers intercaltion and the bulky group of the drug prefers to bind via groove binding.

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DNA Sequence Specific Binding of Some Anticancer Drugs

A Force Field Studies

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Teljes leírás

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