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DNA, Words and Models

Name: DNA, Words and Models
Brand: Cambridge University Press
SKU: 9780521847292
Price: 39102 HUF
Availability: InStock

Statistics of Exceptional Words

Szerző: S. RobinF. RodolpheS. Schbath

Nyelv:

Kötés: Kemény kötésű

Kiadó: Cambridge University Press

Elérhetőség: 50 % esély

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An important problem in computational biology is identifying short DNA sequences (mathematically, 'w...

Információk a könyvről

Szerző

S. RobinF. RodolpheS. Schbath

Nyelv

Angol

Kötés

Könyv - Kemény kötésű

Kiadva

2005

oldal

158

EAN

9780521847292

ISBN

052184729X

Enbook ID

02046802

Kiadó

Cambridge University Press

Súly

386

Méretek

160 x 236 x 13

Teljes leírás

An important problem in computational biology is identifying short DNA sequences (mathematically, 'words') associated to a biological function. One approach consists in determining whether a particular word is simply random or is of statistical significance, for example, because of its frequency or location. This book introduces the mathematical and statistical ideas used in solving this so-called exceptional word problem. It begins with a detailed description of the principal models used in sequence analysis: Markovian models are central here and capture compositional information on the sequence being analysed. There follows an introduction to several statistical methods that are used for finding exceptional words with respect to the model used. The second half of the book is illustrated with numerous examples provided from the analysis of bacterial genomes, making this a practical guide for users facing a real situation and needing to make an adequate procedure choice.