Dynamics of Cancer

Incidence, Inheritance, and Evolution

Szerző: Steven A. Frank

Nyelv:

Kötés: Puha kötésű

Kiadó: Princeton University Press

Elérhetőség: Beszállítói készleten

Küldés 14-21 napon belül

35 306 Ft

The onset of cancer presents one of the most fundamental problems in modern biology. In "Dynamics of...

Információk a könyvről

Szerző

Steven A. Frank

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2007

oldal

400

EAN

9780691133669

ISBN

0691133662

Enbook ID

04641322

Kiadó

Princeton University Press

Súly

576

Méretek

158 x 231 x 26

Teljes leírás

The onset of cancer presents one of the most fundamental problems in modern biology. In "Dynamics of Cancer", Steven Frank produces the first comprehensive analysis of how particular genetic and environmental causes influence the age of onset. The book provides a unique conceptual and historical framework for understanding the causes of cancer and other diseases that increase with age. Using a novel quantitative framework of reliability and multistage breakdown, Frank unifies molecular, demographic, and evolutionary levels of analysis. He interprets a wide variety of observations on the age of cancer onset, the genetic and environmental causes of disease, and the organization of tissues with regard to stem cell biology and somatic mutation. Frank uses new quantitative methods to tackle some of the classic problems in cancer biology and aging: how the rate of increase in the incidence of lung cancer declines after individuals quit smoking, the distinction between the dosage of a chemical carcinogen and the time of exposure, and the role of inherited genetic variation in familial patterns of cancer. This is the only book that presents a full analysis of the age of cancer onset. It is a superb teaching tool and a rich source of ideas for new and experienced researchers. For cancer biologists, population geneticists, evolutionary biologists, and demographers interested in aging, this book provides new insight into disease progression, the inheritance of predisposition to disease, and the evolutionary processes that have shaped organismal design.

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Dynamics of Cancer

Incidence, Inheritance, and Evolution

Információk a könyvről

Teljes leírás

Érdekelheti

Azok a vásárlók, akik ezt a könyvet megvásárolták, a következőket is megvásárolták