Epigenetics, Brain and Behavior

Name: Epigenetics, Brain and Behavior
Brand: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
SKU: 9783642279126
Price: 57894 HUF
Availability: InStock

Szerző: Yves Christen, Paolo Sassone Corsi

Nyelv:

Kötés: Kemény kötésű

Kiadó: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Elérhetőség: Beszállítói készleten

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What lies at the heart of neuronal plasticity? Accumulating evidence points to epigenetics. This wor...

Információk a könyvről

Szerző

Yves Christen, Paolo Sassone Corsi

Nyelv

Angol

Kötés

Könyv - Kemény kötésű

Kiadva

2012

oldal

166

EAN

9783642279126

ISBN

3642279120

Enbook ID

01660454

Kiadó

Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Súly

307

Méretek

155 x 235 x 15

Teljes leírás

What lies at the heart of neuronal plasticity? Accumulating evidence points to epigenetics. This word originally indicated potentially heritable modifications in gene expression that do not involve changes in DNA sequence. Today this definition is much less strict, and epigenetic control is thought to include DNA methylation, histone modifications, histone variants, microRNA metabolic pathways and non-histone proteins modifications. Thus, while neuronal plasticity is rightly thought to be intimately associated to genomic control, it is critical to appreciate that there is much more to the genome than DNA sequence.§Recent years have seen spectacular advances in the field of epigenetics. These have attracted the interest of researchers in many fields and evidence connecting epigenetic regulation to brain functions has been accumulating. Neurons daily convert a variety of external stimuli into rapid or long-lasting changes in gene expression. A variety of studies have centered on the molecular mechanisms implicated in epigenetic control and how these may operate in concert. It will be critical to unravel how specificity is achieved. Importantly, specific modifications seem to mediate both developmental processes and adult brain functions, such as synaptic plasticity and memory. Many aspects of the research in neurosciences and endocrinology during the upcoming decade will be dominated by the deciphering of epigenetic control. This book constitutes a compendium of the most updated views in the field.

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Epigenetics, Brain and Behavior

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