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Extracellular ATP and adenosine as regulators of endothelial cell function

Name: Extracellular ATP and adenosine as regulators of endothelial cell function
Brand: Springer
SKU: 9789400796805
Price: 58960 HUF
Availability: InStock

Implications for health and disease

Szerző: Evgenia Gerasimovskaya, Elzbieta Kaczmarek

Nyelv:

Kötés: Puha kötésű

Kiadó: Springer

Elérhetőség: Beszállítói készleten

Küldés 5-8 napon belül

58 960 Ft

Extracellular purines and pyrimidines (ATP, ADP, UTP and adenosine) are released into the extracellu...

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Szerző

Evgenia Gerasimovskaya, Elzbieta Kaczmarek

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2014

oldal

236

EAN

9789400796805

ISBN

9400796803

Enbook ID

09137665

Kiadó

Springer

Súly

391

Méretek

155 x 13 x 14

Teljes leírás

Extracellular purines and pyrimidines (ATP, ADP, UTP and adenosine) are released into the extracellular milieu in response to a variety of stress conditions and act as important regulators of vascular homeostasis.§§This new book is uniquely focused on the signaling actions of extracellular purines in endothelial cells and the crucial role of extracellular purines in regulation of angiogenesis, vascular tone, cell permeability, wound healing, inflammation and cell-to-cell communication.§This book examines the responses of endothelial cells, originating from various tissues (such as cornea, pancreas and uterus), to extracellular nucleotides and adenosine under physiological and pathological conditions, i.e. pregnancy, hypoxia, hypertension, inflammation and diabetes.§In the book s 12 chapters, the role of purinergic signaling in endothelium-dependent tissue perfusion, regulation of endothelial barrier function, and angiogenesis are discussed. The mechanisms of ATP release and its role in intercellular communication are also presented.§In addition, the book provides the most up to date mechanisms of extracellular nucleotide metabolism by purine-converting ecto-enzymes and their contribution to purinergic signaling in endothelial cells originating from various vascular beds.§§This book is a valuable resource for biomedical research scientists, clinical scientists, graduate students and health science professionals interested in the mechanisms of extracellular purine function in endothelial cells under physiologic and pathologic conditions.§

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Extracellular ATP and adenosine as regulators of endothelial cell function

Implications for health and disease

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