Könyv Fabrication of SR Matrix Tablet for Arthritis Treatment Praveen Kumar

Fabrication of SR Matrix Tablet for Arthritis Treatment

Nyelv: Angol
Kötés: Puha kötésű
Elérhetőség: Beszállítói készleten
Küldés 5-8 napon belül
17 195 Ft
Leflunomide is a disease modifying anti-rheumatic drug (DMARD), which effectively reduces the signs...

Információk a könyvről

Nyelv
Angol
Kötés
Könyv - Puha kötésű
Kiadva
2017
oldal
96
EAN
9783330324664
ISBN
333032466X
Enbook ID
16626222
Súly
159
Méretek
150 x 220 x 6

Teljes leírás

Leflunomide is a disease modifying anti-rheumatic drug (DMARD), which effectively reduces the signs and symptoms of active rheumatoid arthritis (RA) in adults, while inhibiting joint damage and improving physical function. Direct compression was employed for the formulation of tablets. The powder blends of different tablet formulations were screened for preformulation studies like angle of repose, loose bulk density, tapped density, compressibility index and hausner's ratio. The tablets were tested for physical characteristics such as thickness, hardness, friability, weight variation and drug content. The matrix swelling behavior was also investigated. As the time increases, the swelling index was increased; later on it decreases gradually due to dissolution of outermost gelled layer of tablet into dissolution medium. All the evaluated physical parameters of the fabricated tablets were found to be within the acceptable limits.

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