Fragment Based Drug Design

Tools, Practical Approaches, and Examples

Szerző: Lawrence C. Kuo

Nyelv:

Kötés: Kemény kötésű

Kiadó: Elsevier Science Publishing Co Inc

Elérhetőség: Kiadói készleten rendelésre

Küldés 28-34 napon belül

60 321 Ft

There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date...

Információk a könyvről

Szerző

Lawrence C. Kuo

Nyelv

Angol

Kötés

Könyv - Kemény kötésű

Kiadva

2011

oldal

645

EAN

9780123812742

ISBN

0123812747

Enbook ID

04494482

Kiadó

Elsevier Science Publishing Co Inc

Súly

1138

Méretek

238 x 160 x 40

Teljes leírás

There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD. Also elaborated by experienced researchers in FBDD are sample preparations of fragments, proteins, and GPCR as well as examples of how to generate leads from hits. Offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD

Érdekelheti

Azok a vásárlók, akik ezt a könyvet megvásárolták, a következőket is megvásárolták

Leggyakrabban keresett

Categories

Authors

Publishers

Termékek

Termékek

Leggyakrabban keresett

Categories

Authors

Publishers

Termékek

Termékek

Fragment Based Drug Design

Tools, Practical Approaches, and Examples

Információk a könyvről

Teljes leírás

Érdekelheti

Azok a vásárlók, akik ezt a könyvet megvásárolták, a következőket is megvásárolták