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Könyv Graves' Disease Basil Rapoport

Graves' Disease

Pathogenesis and Treatment

Szerző: Basil Rapoport, Sandra M. McLachlan
Nyelv: Angol
Kötés: Kemény kötésű
Kiadó: Springer, Berlin
Elérhetőség: Beszállítói készleten alacsony példányszámban
Küldés 11-15 napon belül
62 139 Ft
From the perspective of the investigator, Graves' disease is a fascinating disorder with unique feat...

Információk a könyvről

Szerző
Basil Rapoport, Sandra M. McLachlan
Nyelv
Angol
Kötés
Könyv - Kemény kötésű
Kiadva
2000
oldal
307
EAN
9780792377900
ISBN
0792377907
Enbook ID
05251007
Kiadó
Springer, Berlin
Súly
630
Méretek
170 x 244 x 19

Teljes leírás

From the perspective of the investigator, Graves' disease is a fascinating disorder with unique features and opportunities for study. The discovery in 1956 that Graves' disease was caused by a humoral factor, later shown to be an antibody to the TSH receptor, was a triumph for modern investigative medicine. Rapid progress is now being made in (i) understanding the molecular interaction between autoantibodies and the TSH receptor, (ii) identifying the genes that contribute to the predisposition to disease, (iii) developing an animal model of Graves' disease, and (iv) identifying the long-sought orbital antigen in ophthalmopathy. From the clinical standpoint, although Graves' disease is eminently treatable, there is no definitive cure. None of the therapeutic options are ideal. It is hoped that rapid progress in understanding the pathogenesis of the disease will lead to the ultimate goal of some form of immunotherapy that will make antithyroid drugs, radioiodine and thyroidectomy obsolete. The chapters in Graves' Disease: Pathogenesis and Treatment represent the viewpoints of many prominent clinicians and investigators working in the field. The editors are grateful for their contributions which cover an unusually comprehensive compendium of subjects relating to the disease.

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