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Könyv Graves' Disease Sandra M. McLachlan

Graves' Disease

Pathogenesis and Treatment

Szerző: Sandra M. McLachlan, Basil Rapoport
Nyelv: Angol
Kötés: Puha kötésű
Kiadó: Springer-Verlag New York Inc.
Elérhetőség: Beszállítói készleten alacsony példányszámban
Küldés 13-18 napon belül
62 849 Ft
From the perspective of the investigator, Graves' disease is a fascinating disorder with unique feat...

Információk a könyvről

Szerző
Sandra M. McLachlan, Basil Rapoport
Nyelv
Angol
Kötés
Könyv - Puha kötésű
Kiadva
2012
oldal
307
EAN
9781461369837
ISBN
1461369835
Enbook ID
06796722
Kiadó
Springer-Verlag New York Inc.
Súly
498
Méretek
155 x 235 x 17

Teljes leírás

From the perspective of the investigator, Graves' disease is a fascinating disorder with unique features and opportunities for study. The discovery in 1956 that Graves' disease was caused by a humoral factor, later shown to be an antibody to the TSH receptor, was a triumph for modern investigative medicine. Rapid progress is now being made in (i) understanding the molecular interaction between autoantibodies and the TSH receptor, (ii) identifying the genes that contribute to the predisposition to disease, (iii) developing an animal model of Graves' disease, and (iv) identifying the long-sought orbital antigen in ophthalmopathy. From the clinical standpoint, although Graves' disease is eminently treatable, there is no definitive cure. None of the therapeutic options are ideal. It is hoped that rapid progress in understanding the pathogenesis of the disease will lead to the ultimate goal of some form of immunotherapy that will make antithyroid drugs, radioiodine and thyroidectomy obsolete. §The chapters in Graves' Disease: Pathogenesis and Treatment represent the viewpoints of many prominent clinicians and investigators working in the field. The editors are grateful for their contributions which cover an unusually comprehensive compendium of subjects relating to the disease.

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