Könyv Histone Recognition Ming-Ming Zhou

Histone Recognition

Szerző: Ming-Ming Zhou
Nyelv: Angol
Kötés: Kemény kötésű
Elérhetőség: Beszállítói készleten
Küldés 10-13 napon belül
38 537 Ft
This book provides a timely review of the role of histone modifications in epigenetic control of gen...

Információk a könyvről

Szerző
Nyelv
Angol
Kötés
Könyv - Kemény kötésű
Kiadva
2015
oldal
282
EAN
9783319181011
ISBN
3319181017
Enbook ID
09255758
Súly
720
Méretek
155 x 235 x 243

Teljes leírás

This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout of histone PTMs by tandem epigenome reader domains; genome-wide profiling of histone PTM interactions; small molecule modulation of histone PTM interactions and their potential as a new approach to therapeutic intervention in human diseases. All chapters were written by leading scientists who made the original key discoveries of the structure and mechanism of evolutionarily conserved reader domains, which serve to direct gene transcription in chromatin through interactions with DNA-packing histones in a PTM-sensitive manner.§

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