Könyv Hormonal Regulation of Mammary Tumors Benjamin Leung

Hormonal Regulation of Mammary Tumors

Volume II: Peptide and Other Hormones

Szerző: Benjamin Leung
Nyelv: Angol
Kötés: Puha kötésű
Kiadó: Springer
Elérhetőség: Beszállítói készleten
Küldés 5-8 napon belül
19 694 Ft
The concept that hormones influence tumor growth originated in 1889 with the proposal of Albert Schi...

Információk a könyvről

Szerző
Nyelv
Angol
Kötés
Könyv - Puha kötésű
Kiadva
2012
oldal
283
EAN
9789401180474
ISBN
9401180474
Enbook ID
02730444
Kiadó
Súly
384
Méretek
140 x 216 x 17

Teljes leírás

The concept that hormones influence tumor growth originated in 1889 with the proposal of Albert Schinzinger who suggested that breast cancer is related to the ovaries. Several years later, Sir George Beatson observed that remission of disseminated breast cancer could be achieved in premenopausal patients by performing bilateral oophorectomy. As a result of the contri butions of Hedley Atkins, Charles Huggins and others, additive and ablative hormonal therapies have been widely used for the treatment of advanced breast cancers for several decades. Model systems to study the effects of hormones on growth and regression of breast tumors have been available for many years; however, the complexities of the hormonal environment have rendered in vivo studies difficult in man and experimental animals. Recently, the availability of long-term cultures of breast cancer cells has stimulated many investigators to use these cell lines to unravel the mechanisms of hormone action. Because of the extreme diversity and complexity of advances regarding the endocrinology of the breast and breast cancers, a multi-authored review was deemed necessary. It has been gratifying to receive contributions from many noted scholars. In Volume I of this monograph, the influence of steroid hormones and their antagonists upon normal and neoplastic tissues of the mammary gland are presented. In Volume II, the effects of peptide and other hormones are reviewed.

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