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Könyv Hyperbranched Polydendrons Fiona Hatton

Hyperbranched Polydendrons

A New Macromolecular Architecture

Szerző: Fiona Hatton
Nyelv: Angol
Kötés: Puha kötésű
Kiadó: Springer International Publishing AG
Elérhetőség: Beszállítói készleten
Küldés 5-8 napon belül
39 357 Ft
This thesis outlines the first synthesis of a new complex branched polymer architecture that aims to...

Információk a könyvről

Szerző
Fiona Hatton
Nyelv
Angol
Kötés
Könyv - Puha kötésű
Kiadva
2016
oldal
260
EAN
9783319369792
ISBN
3319369792
Enbook ID
15194073
Kiadó
Springer International Publishing AG
Súly
4336
Méretek
155 x 235 x 16

Teljes leírás

This thesis outlines the first synthesis of a new complex branched polymer architecture that aims to combine the benefits of dendrimers with the simplicity of conventional polymerisation. There is no other available literature on these remarkable materials, dubbed hyperbranched polydendrons, due to their novelty. The new materials were shown to have very high molecular weights (1,000,000 g/mol), exceptional self-assembly and encapsulation behaviour and unparalleled functionalisation capabilities, and were studied pharmacologically to determine their potential as oral nanomedicine candidates. The detailed investigation of the chemical variables involved in synthesising hyperbranched polydendrons has shown that their self-assembly and pharmacological behaviour can be turned on and off and fine-tuned by altering the composition of the materials. The permeation of the self-assembled particles through model gut epithelium suggests the potential for oral dosing of drug loaded nanomedicines that result in circulating nanoparticles - a research goal that is currently being pursued by several groups around the globe.

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