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Könyv LC/MS Applications in Drug Development Mike S. Lee

LC/MS Applications in Drug Development

Szerző: Mike S. Lee
Nyelv: Angol
Kötés: Kemény kötésű
Kiadó: John Wiley & Sons Inc
Elérhetőség: Beszállítói készleten alacsony példányszámban
Küldés 11-15 napon belül
68 185 Ft
Breakthroughs in combinatorial chemistry and molecular biology, as well as an overall industry trend...

Információk a könyvről

Szerző
Mike S. Lee
Nyelv
Angol
Kötés
Könyv - Kemény kötésű
Kiadva
2002
oldal
256
EAN
9780471405207
ISBN
0471405205
Enbook ID
04890611
Kiadó
John Wiley & Sons Inc
Súly
494
Méretek
162 x 243 x 14

Teljes leírás

Breakthroughs in combinatorial chemistry and molecular biology, as well as an overall industry trend toward accelerated development, mean the rate of sample generation now far exceeds the rate of sample analysis in the pursuit of producing new and better pharmaceuticals. LC/MS is an analytical tool that helps the researcher identify the most promising sample early in the selection process, effectively creating a shortcut to finding new drugs. This book is the first to describe LC/MS applications within the context of drug development, including the discovery, preclinical, clinical, and manufacturing phases. In addition to the thorough technical analysis of this tool, LC/MS Applications in Drug Development provides perspective on the significant changes in strategies for pharmaceutical analysis. A process overview of drug development from an analytical point of view is provided along with essential data required to successfully bring a drug to market. The incorporation of LC/MS is illustrated from target to product. Chapters pertaining to the discovery process itself include:* Proteomics* Glycoprotein Mapping* Natural Products Dereplication* Lead Identification Screening* Open-Access LC/MS* In Vitro Drug Screening Written for both the analytical chemist who uses LC/MS applications and the pharmaceutical scientist who works with the drugs they produce, LC/MS Applications in Drug Development is the premier reference on the subject.

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