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Könyv Leucocyte Trafficking A. Hamann

Leucocyte Trafficking

The Role of Fucosyltransferases and Selectins

Szerző: A. Hamann, Khusru Asadullah, A. Schottelius
Nyelv: Angol
Kötés: Puha kötésű
Kiadó: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Elérhetőség: Beszállítói készleten alacsony példányszámban
Küldés 13-18 napon belül
61 830 Ft
An essential component of inflammation is the migration of circulating leukocytes from blood into ti...

Információk a könyvről

Szerző
A. Hamann, Khusru Asadullah, A. Schottelius
Nyelv
Angol
Kötés
Könyv - Puha kötésű
Kiadva
2013
oldal
242
EAN
9783662053997
ISBN
3662053993
Enbook ID
02176289
Kiadó
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Súly
339
Méretek
148 x 14 x 15

Teljes leírás

An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.§

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