Microbial Gene Essentiality: Protocols and Bioinformatics

Name: Microbial Gene Essentiality: Protocols and Bioinformatics
Brand: Humana Press Inc.
SKU: 9781617375293
Price: 40970 HUF
Availability: InStock

Szerző: Andrei L. Osterman, Svetlana Y. Gerdes

Nyelv:

Kötés: Puha kötésű

Kiadó: Humana Press Inc.

Elérhetőség: Beszállítói készleten alacsony példányszámban

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This book contains a comprehensive collection of experimental and computational strategies and techn...

Információk a könyvről

Szerző

Andrei L. Osterman, Svetlana Y. Gerdes

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2010

oldal

486

EAN

9781617375293

ISBN

1617375292

Enbook ID

01432143

Kiadó

Humana Press Inc.

Súly

942

Méretek

155 x 235 x 26

Teljes leírás

This book contains a comprehensive collection of experimental and computational strategies and techniques for microbial genome-scale essentiality studies, developed and presented by the leading groups in the field. It contains detailed description of the procedures, discussion of potential difficulties and failures. All protocols follow the successful Methods in Molecular Biology series format.Microbial Gene Essentiality: Protocols and Bioinformatics contains a comprehensive collection of experimental and computational strategies and techniques for microbial genome-scale essentiality studies, developed and presented by the leading groups in the field. In addition to wet-lab protocols, the book describes (i) statistical methods essential for planning successful large-scale essentiality screens, as well for data evaluation and analysis; (ii) in-silico prediction of gene essentiality using genome-scale reconstructed metabolic models; and (iii) data integration and comparative analysis in the context of genomic databases. This volume provides researchers with a first-stop guide for choosing the most appropriate strategy for planned essentiality studies. Experimental and computational aspects are equally important in genome-scale gene essentiality analysis, as in all other genomic technologies, and Microbial Gene Essentiality: Protocols and Bioinformatics reflects both of these aspects. All protocols follow the successful Methods in Molecular Biology series format, each offering an introduction outlining the principles behind the techniques, step-by-step instructions, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding pitfalls, and are intended for both novice and expert scientists.

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Microbial Gene Essentiality: Protocols and Bioinformatics

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