Könyv Mitochondrial DNA Mutations in Aging, Disease and Cancer Keshav K. Singh

Mitochondrial DNA Mutations in Aging, Disease and Cancer

Szerző: Keshav K. Singh
Nyelv: Angol
Kötés: Puha kötésű
Elérhetőség: Beszállítói készleten
Küldés 5-8 napon belül
39 356 Ft
Many human genetic diseases associated with blood, brain, colon, ear, eye, heart, kidney, liver, mus...

Információk a könyvről

Szerző
Nyelv
Angol
Kötés
Könyv - Puha kötésű
Kiadva
2013
oldal
412
EAN
9783662125113
ISBN
3662125110
Enbook ID
05287446
Súly
748
Méretek
170 x 244 x 24

Teljes leírás

Many human genetic diseases associated with blood, brain, colon, ear, eye, heart, kidney, liver, muscle, and pancreas are caused by mutations in mitochondrial DNA. Mutations in DNA can result in defects of the electron transport complexes, intermediates of the tricarboxylic acid cycle and substrate transport. The clinical manifestation of these diseases often involves muscle and the nervous system. Mitochondrial DNA mutations have now been associated with aging as well as age-related degenerative diseases such as Parkinson's, Alzheimer's, and Huntington's diseases. Changes in structure, function, and a number of mitochondria play an important role in carcinogenesis. Furthermore, the role of mitochondria in the execution of programmed cell death or apoptosis has been recognized recently.

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