Molecular Cytogenetics

Name: Molecular Cytogenetics
Brand: Springer, Berlin
SKU: 9781617373008
Price: 61453 HUF
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Protocols and Applications

Szerző: Yao-Shan Fan

Nyelv:

Kötés: Puha kötésű

Kiadó: Springer, Berlin

Elérhetőség: Beszállítói készleten alacsony példányszámban

Küldés 11-15 napon belül

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The new techniques of molecular cytogenetics, mainly fluorescence in situ hybridization (FISH) of DN...

Információk a könyvről

Szerző

Yao-Shan Fan

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2010

oldal

414

EAN

9781617373008

ISBN

1617373001

Enbook ID

02717286

Kiadó

Springer, Berlin

Súly

620

Méretek

152 x 22 x 23

Teljes leírás

The new techniques of molecular cytogenetics, mainly fluorescence in situ hybridization (FISH) of DNA probes to metaphase chromosomes or interphase nuclei, have been developed in the past two decades. Many FISH techniques have been implemented for diagnostic services, whereas some others are mainly used for investigational purposes. Several hundreds of FISH probes and hybridization kits are now commercially available, and the list is growing rapidly. FISH has been widely used as a powerful diagnostic tool in many areas of medicine including pediatrics, medical genetics, maternal fetal medicine, reproductive medicine, pathology, hematology, and oncology. Frequently, a physician may be puzzled by the variety of FISH techniques and wonder what test to order. It is not uncommon that a sample is referred to a laboratory for FISH without indicating a specific test. On the other hand, a cytogeneticist or a technologist in a laboratory needs, from case to case, to determine which procedure to perform and which probe to use for an informative result. To obtain the best results, one must use the right DNA probes and have reliable protocols and measures of quality assurance in place. Also, one must have sufficient knowledge in both traditional and molecular cytogenetics, as well as the particular areas of medicine for which the test is used in order to appropriately interpret the FISH results, and to correlate them with clinical diagnosis, treatment, and prognosis.

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Molecular Cytogenetics

Protocols and Applications

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