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Könyv Molecular Neuropharmacology Arne Schousboe

Molecular Neuropharmacology

Strategies and Methods

Szerző: Arne Schousboe, Hans Bräuner-Osborne
Nyelv: Angol
Kötés: Puha kötésű
Kiadó: Humana Press Inc.
Elérhetőség: Beszállítói készleten
Küldés 5-8 napon belül
54 524 Ft
A powerful collection of readily reproducible cutting-edge techniques for characterizing the ligand...

Információk a könyvről

Szerző
Arne Schousboe, Hans Bräuner-Osborne
Nyelv
Angol
Kötés
Könyv - Puha kötésű
Kiadva
2010
oldal
271
EAN
9781617373848
ISBN
1617373842
Enbook ID
01432030
Kiadó
Humana Press Inc.
Súly
618
Méretek
178 x 254 x 16

Teljes leírás

A powerful collection of readily reproducible cutting-edge techniques for characterizing the ligand or substrate binding of neurotransmitter receptors and transporters. The procedures cover interdisciplinary interactions for monoamine transporters, amino acid transporters, ionotropic receptors, metabotropic glutamate receptors, GABA receptors, and other G protein-coupled receptors. By illuminating how neurons in the central nervous communicate with other, these techniques can lead to the development of novel therapeutic strategies for neurological diseases.The ability to clone large numbers of receptors and transporters for neurotransmitters, and then to produce specific mutations of these proteins, has yielded significant understanding of their pharmacological and functional properties, with still deeper insight obtainable through the application of computational and medicinal chemistry. In Molecular Neuropharmacology: Strategies and Methods, leading neuroscience investigators combine advanced chemistry with molecular modeling to produce a powerful collection of cutting-edge techniques for characterizing the ligand or substrate binding of neurotransmitter receptors and transporters. The procedures cover interdisciplinary interactions for monoamine transporters, amino acid transporters, ionotropic receptors, metabotropic glutamate receptors, GABA receptors, and other G protein-coupled receptors. Information about x-ray crystallographic analyses is included whenever available. §State-of-the-art and highly practical, Molecular Neuropharmacology: Strategies and Methods provides detailed accounts of the tools needed to understand how CNS neurons communicate and promises the development of novel therapeutic agents and strategies for many neurological diseases.

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