Nano-patterning of a-C:H surfaces for control of protein adsorption

Name: Nano-patterning of a-C:H surfaces for control of protein adsorption
Brand: LAP Lambert Academic Publishing
SKU: 9783659754203
Price: 24791 HUF
Availability: InStock

Szerző: Muhammad Zeeshan Mughal

Nyelv:

Kötés: Puha kötésű

Kiadó: LAP Lambert Academic Publishing

Elérhetőség: Beszállítói készleten

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Predicting how proteins fold and adsorb onto surfaces is a complex problem of strong relevance to th...

Információk a könyvről

Szerző

Muhammad Zeeshan Mughal

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2016

oldal

168

EAN

9783659754203

Enbook ID

02983351

Kiadó

LAP Lambert Academic Publishing

Súly

268

Méretek

150 x 220 x 10

Teljes leírás

Predicting how proteins fold and adsorb onto surfaces is a complex problem of strong relevance to the health and environmental sectors. It is often examined within the larger context of cellular adhesion, however, understanding adsorption of proteins is complicated because of many factors: cell sensing and intercellular signaling, surface topography and cytoskeleton. Hence, proteins-only studies are valuable to investigate bio-film formation, protein condensation diseases and the toxicity of nano-materials. This book presents a systematic investigation of protein adsorption on nano-patterned hydrogenated amorphous carbon (a-C:H) thin films. The first half deals with the preparation and analysis of a-C:H patterns by focused ion beam (FIB) milling and atomic force microscopy (AFM) nanoindentation. The second half investigates protein adsorption for four different protein/solvent systems. The results showed that nano-patterned model surfaces are useful to study and control protein adsorption, while the methods developed can be extended to other patterning techniques and protein systems to study independently the influence of topography and composition on protein adsorption.

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Nano-patterning of a-C:H surfaces for control of protein adsorption

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