New Applications of NMR in Drug Discovery and Development

Szerző: Leoncio Garrido

Nyelv:

Kötés: Kemény kötésű

Kiadó: Royal Society Of Chemistry

Elérhetőség: Beszállítói készleten

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This book presents a review of recent developments in NMR applications in pharmaceutical research. C...

Információk a könyvről

Szerző

Leoncio Garrido

Nyelv

Angol

Kötés

Könyv - Kemény kötésű

Kiadva

2013

oldal

565

EAN

9781849734448

ISBN

1849734445

Enbook ID

05107313

Kiadó

Royal Society Of Chemistry

Súly

1022

Méretek

156 x 234 x 40

Teljes leírás

This book presents a review of recent developments in NMR applications in pharmaceutical research. Consideration is given to consolidated and emerging techniques and methods, many of which are not yet widely applied but are likely to provide new opportunities for drug design. The first part of the book is dedicated to the description of NMR as a tool for the analysis of chemicals and their interactions with targets. The next seven chapters describe NMR approaches to investigate in vivo models of interest in drug discovery and development, with the attention focused on anatomy, function, metabolism and molecular-cellular aspects. Finally, consideration is given to the application of in vivo NMR to the identification and characterization of biomarkers with the aim of monitoring the outcome of therapeutic intervention in selected human diseases, including the study of drug metabolism and toxicity. Aimed at NMR spectroscopists, pharmacologists, imaging researchers and pharmaceutical scientists, this title will be invaluable at putting NMR in context within its role in drug discovery and development. This resource will be essential reading for those both new and already active in these areas.

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New Applications of NMR in Drug Discovery and Development

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