Könyv NMDA Antagonists as Potential Analgesic Drugs Dalip J.S. Sirinathsinghji

NMDA Antagonists as Potential Analgesic Drugs

Nyelv: Angol
Kötés: Kemény kötésű
Elérhetőség: Beszállítói készleten
Küldés 10-13 napon belül
39 428 Ft
There is now considerable preclinical evidence that glutamate acting via the NMDA receptor is involv...

Információk a könyvről

Nyelv
Angol
Kötés
Könyv - Kemény kötésű
Kiadva
2002
oldal
194
EAN
9783764360115
ISBN
3764360119
Enbook ID
01716394
Súly
600
Méretek
155 x 235 x 17

Teljes leírás

There is now considerable preclinical evidence that glutamate acting via the NMDA receptor is involved in the transmission of nociceptive information and in the triggering mechanisms for hyperalgesia and allodynia. This evidence allows rational development of a new class of analgesic drugs that act as antagonists of the NMDA receptor, supported by emerging evidence with existing excitatory amino acid antagonists.§Leading scientists in excitatory amino acid and analgesia research have compiled in this volume the most recent information on molecular biology, physiology and pharmacology of NMDA receptors, their neuroanatomical localisation within specific neural pathways involved in nociception, and experimental and clinical evidence demonstrating the potential of receptor antagonists of NMDA and other excitatory amino acids in the treatment of pain states.

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