Patho-Epigenetics of Infectious Disease

Name: Patho-Epigenetics of Infectious Disease
Brand: Springer International Publishing AG
SKU: 9783319247366
Price: 39475 HUF
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Szerző: Janos Minarovits, Hans Helmut Niller

Nyelv:

Kötés: Kemény kötésű

Kiadó: Springer International Publishing AG

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Epigenetic modification of cellular genomes is a fascinating means of regulating tissue- and cell ty...

Információk a könyvről

Szerző

Janos Minarovits, Hans Helmut Niller

Nyelv

Angol

Kötés

Könyv - Kemény kötésű

Kiadva

2015

oldal

137

EAN

9783319247366

ISBN

3319247360

Enbook ID

09523638

Kiadó

Springer International Publishing AG

Súly

4465

Méretek

178 x 254 x 13

Teljes leírás

Epigenetic modification of cellular genomes is a fascinating means of regulating tissue- and cell type-specific gene expression in all developmental stages of the life of an organism. Carefully orchestrated processes, such as DNA methylation and a plenitude of specific histone modifications secure the faithful transmission of gene expression patterns to progeny cells. Upon chronic infection, the epigenetic cellular balance can become disrupted and, in the long run, through the epigenetic reprogramming of host cell genomes, contribute to the malignant conversion of formerly healthy cells, in many cases preceded by the establishment of an epigenetic field of cancerization. The present volume undertakes to highlight the interactions of infectious pathogens and their effector molecules with the epigenetic regulatory machinery of the cell. Clearly, the recent take-off of epigenetics research did not leave Research on Infectious Diseases and Infection-Associated Cancer untouched. This resulted in a great many of clinically relevant data on understanding the molecular mechanisms of chronic infectious disease. Infectious pathogen- and disease-specific epigenetic alterations are already being used for the early detection of malignant disease and for the prediction of chemotherapy resistance or response to treatment.§

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Patho-Epigenetics of Infectious Disease

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