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Physiology of Astroglia

Name: Physiology of Astroglia
Brand: Morgan & Claypool Publishers
SKU: 9781615046720
Price: 29996 HUF
Availability: InStock

Channels, Receptors, Transporters, Ion Signaling and Gliotransmission

Szerző: Alexei Verkhratsky, Vladimir Parpura

Nyelv:

Kötés: Puha kötésű

Kiadó: Morgan & Claypool Publishers

Elérhetőség: Beszállítói készleten

Küldés 14-21 napon belül

29 996 Ft

Astrocytes can be defined as the glia inhabiting the nervous system with the main function in the ma...

Információk a könyvről

Szerző

Alexei Verkhratsky, Vladimir Parpura

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2015

oldal

172

EAN

9781615046720

ISBN

9781615046720

Enbook ID

10836572

Kiadó

Morgan & Claypool Publishers

Súly

336

Méretek

234 x 192 x 11

Teljes leírás

Astrocytes can be defined as the glia inhabiting the nervous system with the main function in the maintenance of nervous tissue homeostasis. Classified into several types according to their morphological appearance, many of astrocytes form a reticular structure known as astroglial syncytium, owing to their coupling via intercellular channels organized into gap junctions. Not only do astrocytes establish such homocellular contacts, but they also engage in intimate heterocellular interactions with neurons, most notably at synaptic sites. As synaptic structures house the very core of information transfer and processing in the nervous system, astroglial perisynaptic positioning assures that these glial cells can nourish neurons and establish bidirectional communication with them, functions outlined in the concepts of the astrocytic cradle and multi-partite synapse, respectively. Astrocytes possess a rich assortment of ligand receptors, ion and water channels, and ion and ligand transporters, which collectively contribute to astrocytic control of homeostasis and excitability. Astroglia control glutamate and adenosine homeostasis to exert modulatory actions affecting the real-time operation of synapses. Fluctuations of intracellular calcium can lead to the release of various chemical transmitters from astrocytes through a process termed gliotransmission. Sodium fluctuations are closely associated to those of calcium with both dynamic events interfacing signaling and metabolism. Astrocytes appear fully integrated into the brain cellular circuitry, being an indispensable part of neural networks.

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Leggyakrabban keresett

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Authors

Publishers

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Termékek

Physiology of Astroglia

Channels, Receptors, Transporters, Ion Signaling and Gliotransmission

Információk a könyvről

Teljes leírás

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