Polyamine Drug Discovery

Szerző: Patrick Woster

Nyelv:

Kötés: Kemény kötésű

Kiadó: Royal Society Of Chemistry

Elérhetőség: Beszállítói készleten alacsony példányszámban

Küldés 9-15 napon belül

68 710 Ft

Polyamines are ubiquitous molecules that are involved in a number of important cellular processes. A...

Információk a könyvről

Szerző

Patrick Woster

Nyelv

Angol

Kötés

Könyv - Kemény kötésű

Kiadva

2011

oldal

302

EAN

9781849731904

ISBN

184973190X

Enbook ID

04416368

Kiadó

Royal Society Of Chemistry

Súly

600

Méretek

239 x 161 x 22

Teljes leírás

Polyamines are ubiquitous molecules that are involved in a number of important cellular processes. Aberrations in their function or metabolism play a role in diseases such as cancer and parasitic infection. A number of validated drug targets have been identified, including enzymes in the polyamine biosynthetic and catabolic pathways and the S-adenosylmethionine synthetic and salvage pathways. Polyamine Drug Discovery is the first comprehensive volume to cover all aspects of the design and development of potential therapeutics targeting polyamine metabolism. The book details research progress from 1975 to the present date and discusses the design and use of polyamine metabolism inhibitors as therapeutic agents. Various polyamine-containing drugs are described that can be used in chemotherapy, and as treatments for infections including trypanosomiasis, leishmaniasis and malaria. Finally, the roles of polyamine analogues in chemoprevention, polyamine-containing vectors for gene delivery, and the design of polyamine-based epigenetic modulators are detailed. Each chapter addresses a different aspect of polyamine drug discovery and all are written by medicinal and biological chemists with particular expertise in developing agents that modulate polyamine metabolism or function. The book will increase the visibility of polyamine drug discovery among pharmaceutical researchers and provide a valuable reference for everyone working in the field.

Érdekelheti

Azok a vásárlók, akik ezt a könyvet megvásárolták, a következőket is megvásárolták

Leggyakrabban keresett

Categories

Authors

Publishers

Termékek

Termékek

Leggyakrabban keresett

Categories

Authors

Publishers

Termékek

Termékek

Polyamine Drug Discovery

Információk a könyvről

Teljes leírás

Érdekelheti

Summoner

New Science of Geology

Collected Papers I

Natural History of the British Lepidoptera

Azok a vásárlók, akik ezt a könyvet megvásárolták, a következőket is megvásárolták

Der Ursprung Der Culturpflanzen (1884)

Kariera Nikodema Dyzmy