Protective Immunity against Hepatitis C

Name: Protective Immunity against Hepatitis C
Brand: VDM Verlag Dr. Müller
SKU: 9783639210514
Price: 27694 HUF
Availability: InStock

CORRELATES OF PROTECTIVE IMMUNITY IN INDIVIDUALS WHO ARE EXPOSED TO HEPATITIS C BUT APPEAR UNINFECTED

Szerző: Lisa Elliott

Nyelv:

Kötés: Puha kötésű

Kiadó: VDM Verlag Dr. Müller

Elérhetőség: Kiadói készleten rendelésre

Küldés 17-27 napon belül

27 694 Ft

A small subset of individuals who are exposed to HCV do not develop anti-HCV antibodies, persistent...

Információk a könyvről

Szerző

Lisa Elliott

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2009

oldal

324

EAN

9783639210514

Enbook ID

06828976

Kiadó

VDM Verlag Dr. Müller

Súly

499

Méretek

150 x 220 x 19

Teljes leírás

A small subset of individuals who are exposed to HCV do not develop anti-HCV antibodies, persistent viraemia or chronic hepatitis despite generating HCV-specific CD4+ and CD8+ T cells. These individuals are believed to develop an immune response which rapidly clears viraemia prior to the induction of an antibody response. Cellular immune responses were evaluated in 23 infants born to HCV positive women. Responses were detected in 1/11 infants born to viraemic mothers, with cytokine production observed in an additional 3/5 infants. Responses were also assessed in multiply transfused subjects with thalassaemia. Responses were detected in 6/13 chronically infected subjects (46%), 4/7 subjects who had cleared infection (71%), and 14/17 seronegative subjects (82%). The third cohort were 41 seronegative injecting drug users, with responses detected in 6 (15%). HCV specific cellular immune responses in seronegative subjects were generally broad in specificity, with a generally Th-1 biased pattern of cytokine production. The findings suggest that responses can be maintained for decades after exposure, and may provide protection against repeated exposures.

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Protective Immunity against Hepatitis C

CORRELATES OF PROTECTIVE IMMUNITY IN INDIVIDUALS WHO ARE EXPOSED TO HEPATITIS C BUT APPEAR UNINFECTED

Információk a könyvről

Teljes leírás

Érdekelheti

Azok a vásárlók, akik ezt a könyvet megvásárolták, a következőket is megvásárolták