Könyv Protein Targeting Compounds Thomas Böldicke

Protein Targeting Compounds

Prediction, Selection and Activity of Specific Inhibitors

Szerző: Thomas Böldicke
Nyelv: Angol
Kötés: Kemény kötésű
Elérhetőség: 50 % esély
Keressük az egész világon
53 800 Ft
This book presents an overview of the most relevant protein knockdown techniques. Readers will find...

Információk a könyvről

Nyelv
Angol
Kötés
Könyv - Kemény kötésű
Kiadva
2015
oldal
288
EAN
9783319224725
ISBN
3319224727
Enbook ID
09389380
Súly
601
Méretek
155 x 235 x 23

Teljes leírás

This book presents an overview of the most relevant protein knockdown techniques. Readers will find a description of the generation and use of recombinant human antibodies, ER intrabodies and peptides as well as a description of the working mechanism and potential of the inhibitory action of each of these molecules. The book will also describe the selection and activity of a number of phosphatases, aptamers and allosteric modulators, focusing on A G protein coupled receptors. The book starts with a chapter on the in silico prediction of target-inhibitor interactions.§§Key aspects of this book are:§§- Selection strategies for monoclonal and recombinant human antibodies §§- Selection strategies for ER intrabodies, peptides and aptamers §§- Examples of the most efficient inhibitors and their applications in protein biochemistry and cell biology§§- Antibodies for cancer therapy and inhibitors of angiogenesis.§§The book will be of great interesting to scientists and students working in the life sciences on all areas related to protein biology. The variety of methods to modulate the activities of specific proteins which are introduced here will be of great benefit to the reader who is interested in general protein research or to readers who have very specific protein related questions.§

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