Reactive Oxygen Species (ROS) Based Therapeutics

Name: Reactive Oxygen Species (ROS) Based Therapeutics
Brand: LAP Lambert Academic Publishing
SKU: 9783330069152
Price: 12402 HUF
Availability: InStock

Role of ROS in therapeutics and drug resistance in cancer and bacteria

Szerző: Dharmaraja Allimuthu

Nyelv:

Kötés: Puha kötésű

Kiadó: LAP Lambert Academic Publishing

Elérhetőség: Beszállítói készleten

Küldés 5-8 napon belül

12 402 Ft

ROS a "double edged sword": Evading persistent drug resistance in cancer and bacteria is quintessent...

Információk a könyvről

Szerző

Dharmaraja Allimuthu

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2017

oldal

EAN

9783330069152

Enbook ID

16335901

Kiadó

LAP Lambert Academic Publishing

Súly

113

Méretek

150 x 220 x 4

Teljes leírás

ROS a "double edged sword": Evading persistent drug resistance in cancer and bacteria is quintessential to restore health in humans, and impels intervention strategies. A distinct property of the cancer phenotype is enhanced glucose metabolism and oxidative stress. Reactive oxygen species (ROS) are metabolic byproducts of aerobic respiration and are responsible for maintaining redox homeostasis in cells. Redox balance and oxidative stress are orchestrated by antioxidant enzymes, reduced thiols and NADP(H) cofactors, which is critical for cancer cells survival and progression. Similarly, Escherichia coli (E. coli) and life-threatening infectious pathogens such as Staphylococcus aureus (SA) and Mycobacterium tuberculosis (Mtb) are appreciably sensitive to changes in the intracellular oxidative environment. Thus, small molecules that modulate antioxidant levels and/or enhance intracellular ROS could disturb the cellular oxidative environment and induce cell death, and hence could serve as novel therapeutics. Presented here are a collection of approaches that involve ROS modulation in cells as a strategy to target cancer and bacteria.

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Reactive Oxygen Species (ROS) Based Therapeutics

Role of ROS in therapeutics and drug resistance in cancer and bacteria

Információk a könyvről

Teljes leírás

Érdekelheti

Azok a vásárlók, akik ezt a könyvet megvásárolták, a következőket is megvásárolták