Role of Matrix Metalloproteinases in Tissue Remodeling

Name: Role of Matrix Metalloproteinases in Tissue Remodeling
Brand: VDM Verlag Dr. Müller
SKU: 9783639207897
Price: 17612 HUF
Availability: InStock

relevance to pathogenesis of restenosis, aortic aneurism, joint and disc degeneration research

Szerző: Leon Margolin

Nyelv:

Kötés: Puha kötésű

Kiadó: VDM Verlag Dr. Müller

Elérhetőség: Kiadói készleten rendelésre

Küldés 17-27 napon belül

17 612 Ft

Matrix metalloproteinases (MMP) are the key enzymes in the pathogenesis of osteoarthritis and inflam...

Információk a könyvről

Szerző

Leon Margolin

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2009

oldal

EAN

9783639207897

Enbook ID

06828751

Kiadó

VDM Verlag Dr. Müller

Méretek

150 x 220 x 5

Teljes leírás

Matrix metalloproteinases (MMP) are the key enzymes in the pathogenesis of osteoarthritis and inflammatory arthritis. This study was performed on the rat common carotid artery model. This model has better accessibility and reliable injury assessment techniques in comparison to articular cartilage. This groundbreaking study shows that MMP inhibition resulted in a significant decrease in the cell proliferation and the remodeling of the extracellular matrix up to 2 months after the MMP injection versus untreated control group and that these effects were associated with a marked reduction in MMP-2 activity. We strongly advocate testing of non hydroxamate type matrix metalloproteinase inhibitors in larger animals and in the clinical setting for degenerative joint and disc disease. Dr. Margolin's "out of the box" thinking, original study design and sharp indepth analysis are a new important step in restenosis, aortic aneurism and metastasis research as well in developing a disease modifying agent for degenerative disc and joint disease.

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Role of Matrix Metalloproteinases in Tissue Remodeling

relevance to pathogenesis of restenosis, aortic aneurism, joint and disc degeneration research

Információk a könyvről

Teljes leírás

Érdekelheti

Azok a vásárlók, akik ezt a könyvet megvásárolták, a következőket is megvásárolták