Seeing the Transplanted Mouse Heart Like Never Before

Name: Seeing the Transplanted Mouse Heart Like Never Before
Brand: VDM Verlag Dr. Mueller E.K.
SKU: 9783836487382
Price: 26935 HUF
Availability: InStock

New Insights Into Experimental Heart Rejection Using Novel Ultrasound Applications

Szerző: Ramy Bishay

Nyelv:

Kötés: Puha kötésű

Kiadó: VDM Verlag Dr. Mueller E.K.

Elérhetőség: Beszállítói készleten

Küldés 14-21 napon belül

26 935 Ft

Heart rejection is a major problem for heart transplant patients. The best strategy for understandin...

Információk a könyvről

Szerző

Ramy Bishay

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2008

oldal

184

EAN

9783836487382

ISBN

3836487381

Enbook ID

06888449

Kiadó

VDM Verlag Dr. Mueller E.K.

Súly

254

Méretek

152 x 229 x 10

Teljes leírás

Heart rejection is a major problem for heart transplant patients. The best strategy for understanding and preventing organ rejection is to study experimental animal models. The popular mouse model of heterotopic cardiac transplantation has been used for over three decades to help investigators understand the pathogenesis of graft rejection and in turn, how novel drugs can attenuate the immune response to transplanted organs. Also, since the genetic blueprint of mice is well-known, specific genes can be modified to study its effect on graft acceptance and tolerance. Despite the large potential for this model, little is known about the physiology, haemodynamics, and morphology of the transplanted heart and there is no method to assess objectively graft survival. This work describes in detail the use of high-frequency ultrasound for investigating the small transplanted mouse heart. For the first time, insights are made into blood flow, the effects of graft rejection, and organ survival with never before seen high-resolution images unachievable with conventional ultrasound. This work will be of significant interest to investigators, clinicians and students in the field. Heart rejection is a major problem for heart transplant patients. The best strategy for understanding and preventing organ rejection is to study experimental animal models.The popular mouse model of heterotopic cardiac transplantation has been used for over three decades to help investigators understand the pathogenesis of graft rejection and in turn, how novel drugs can attenuate the immune response to transplanted organs. Also, since the genetic blueprint of mice is well-known, specific genes can be modified to study its effect on graft acceptance and tolerance. Despite the large potential for this model, little is known about the physiology, haemodynamics, and morphology of the transplanted heart and there is no method to assess objectively graft survival. This work describes in detail the use of high-frequency ultrasound for investigating the small transplanted mouse heart. For the first time, insights are made into blood flow, the effects of graft rejection, and organ survival with never before seen high-resolution images unachievable with conventional ultrasound. This work will be of significant interest to investigators, clinicians and students in the field.

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Seeing the Transplanted Mouse Heart Like Never Before

New Insights Into Experimental Heart Rejection Using Novel Ultrasound Applications

Információk a könyvről

Teljes leírás

Érdekelheti

Azok a vásárlók, akik ezt a könyvet megvásárolták, a következőket is megvásárolták