Könyv Self-Assembled Peptidic Nanostructures Mustafa O. Guler

Self-Assembled Peptidic Nanostructures

Presentation and Recognition of Functional Groups on Self-Assembled Nanostructures

Szerző: Mustafa O. Guler
Nyelv: Angol
Kötés: Puha kötésű
Elérhetőség: Kiadói készleten rendelésre
Küldés 17-27 napon belül
20 682 Ft
Molecular recognition in biology requires appropriate §conformational presentation of ligands and re...

Információk a könyvről

Nyelv
Angol
Kötés
Könyv - Puha kötésű
Kiadva
2009
oldal
152
EAN
9783639127348
Enbook ID
06821500
Méretek
150 x 220 x 9

Teljes leírás

Molecular recognition in biology requires appropriate §conformational presentation of ligands and receptor §binding sites. There has been great interest in §design of materials with biological epitopes that can §induce cellular events important in tissue §regeneration. The use of self-assembly is §particularly attractive because it can allow §biomolecular scaffold formation in situ by delivering §liquids containing the self-assembling molecules to a target tissue site. This book explores self-§assembling peptide amphiphiles (PA) with various §functional groups that assemble to form nanofiber §networks in physiological media. The PA molecules §were designed with a branched architecture to enhance §recognition of bioactive epitopes on the surfaces of §nanofibers. Biotinylated model branched PA systems §for recognition of biotin by avidin on the periphery §of the nanofibers were studied and the branched §architecture enhanced the recognition of biotin by §avidin possibly by changing the packing density of §molecules in the nanofibers. Various PA molecules §were synthesized with branched architectures for §enhanced recognition of biological signals for §cellular adhesion.

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