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Könyv SH Domains Natalya Kurochkina

SH Domains

Structure, Mechanisms and Applications

Szerző: Natalya Kurochkina
Nyelv: Angol
Kötés: Kemény kötésű
Kiadó: Springer International Publishing AG
Elérhetőség: Beszállítói készleten
Küldés 10-13 napon belül
38 497 Ft
This book covers structure, function, and important roles of the SH domains, structure-function rela...

Információk a könyvről

Szerző
Natalya Kurochkina
Nyelv
Angol
Kötés
Könyv - Kemény kötésű
Kiadva
2015
oldal
253
EAN
9783319200972
ISBN
3319200976
Enbook ID
09301131
Kiadó
Springer International Publishing AG
Súly
5207
Méretek
155 x 235 x 244

Teljes leírás

This book covers structure, function, and important roles of the SH domains, structure-function relationships, the versatile nature of their action, mechanisms of aggregation, specificity of interactions, impact of mutations on protein functional dysregulation, and cell signaling. Their involvement in various cellular processes such as migration, invasiveness, actin reorganization, shaping spines, determination of the morphology assembly of fibrils, and mechanotransduction makes these molecules attractive drug targets. Substrates, inhibitors and activators of PTKs present a wide variety of therapeutic agents in the context of delivering treatments for numerous pathologies. The new emerging field of stem cell therapies and design of biomaterials for treatments relies on the directed regulation of stem cell growth, differentiation and morphology, as well as the production of biomimetic scaffolds that respond to programmed signals. Advances in deciphering the mechanisms of action of these important molecules will lead to the implementation and success of their vital applications.§

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