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Könyv Single Nucleotide Polymorphisms Zuben E. Sauna

Single Nucleotide Polymorphisms

Human Variation and a Coming Revolution in Biology and Medicine

Szerző: Zuben E. Sauna, Chava Kimchi-Sarfaty
Nyelv: Angol
Kötés: Kemény kötésű
Kiadó: Springer International Publishing AG
Elérhetőség: Beszállítói készleten
Küldés 10-13 napon belül
56 646 Ft
This book explores the importance of Single Nucleotide Polymorphisms (SNPs) in biomedical research....

Információk a könyvről

Szerző
Zuben E. Sauna, Chava Kimchi-Sarfaty
Nyelv
Angol
Kötés
Könyv - Kemény kötésű
Kiadva
2022
oldal
234
EAN
9783031056147
Enbook ID
38961776
Kiadó
Springer International Publishing AG
Súly
553
Méretek
155 x 235 x 20

Teljes leírás

This book explores the importance of Single Nucleotide Polymorphisms (SNPs) in biomedical research. As SNP technologies have evolved from labor intensive, expensive, time-consuming processes to relatively inexpensive methods, SNP discovery has exploded. In terms of human biology, this research, particularly since the completion of the Human Genome Project, has provided a detailed understanding of evolutionary forces that have generated SNPs. It also has shown how SNPs shape human variation. The ability to inexpensively generate and analyze vast amounts of genetic data is poised to transform our understanding of human evolution and biology. "Single Nucleotide Polymorphisms" covers a broad  survey of SNPs and their classification into synonymous and non-synonymous; the role of SNPs in human disease; case studies providing specific examples of synonymous and non-synonymous SNPs associated with human diseases or affecting therapeutic interventions; mechanisms by which synonymous mutations affect protein levels or protein folding which affect human physiology and response to therapy; and the role of SNPs in personalized medicine. Understanding what SNPs are, how they have been shaped is necessary for an increasingly expanding audience. This research will revolutionize the future of medicine. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

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