Könyv Solid Lipid Nanoparticles Manish Jindal

Solid Lipid Nanoparticles

In-vitro/In-vivo Characterization

Nyelv: Angol
Kötés: Puha kötésű
Kiadó: VDM Verlag
Elérhetőség: Kiadói készleten rendelésre
Küldés 17-27 napon belül
17 499 Ft
Delivery of drugs to the brain is a major challenge due to the presence of the blood brain barrier....

Információk a könyvről

Nyelv
Angol
Kötés
Könyv - Puha kötésű
Kiadva
2011
oldal
96
EAN
9783639324433
ISBN
3639324439
Enbook ID
06839226
Kiadó
Súly
150
Méretek
152 x 229 x 6

Teljes leírás

Delivery of drugs to the brain is a major challenge due to the presence of the blood brain barrier. To reach therapeutic drug level in the brain, nanoparticulate systems are being recently investigated as potential drug carriers due to their high loading capacity, small particle size and ability to bypass the Reticulo Endothelial System. Nanoparticles in fact, are solid colloidal particles ranging in size from 1 to 1000 nm and are composed of macromolecular material which could be polymeric or lipidic. Solid lipid nanoparticles (SLNs) are taken up readily by the brain because of their lipidic nature. The bioacceptable and biodegradable nature of SLNs makes them less toxic as compared to polymeric nanoparticles. SLN have been found to improve the permeability of drug through the blood brain-barrier and is a promising drug targeting system for the treatment of central nervous system disorders.

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