Systematic Exploration of Indolizine-Based Small Fluorescent Molecules

Synthesis, Analysis and Application

Szerző: Youngjun Lee

Nyelv:

Kötés: Kemény kötésű

Kiadó: Springer Verlag, Singapore

Elérhetőség: Beszállítói készleten

Küldés 10-13 napon belül

36 185 Ft

This thesis describes an in-depth study of an indolizine-based fluorophore, from understanding of it...

Információk a könyvről

Szerző

Youngjun Lee

Nyelv

Angol

Kötés

Könyv - Kemény kötésű

Kiadva

2018

oldal

187

EAN

9789811316449

ISBN

9811316449

Enbook ID

19733635

Kiadó

Springer Verlag, Singapore

Súly

494

Méretek

155 x 235 x 17

Teljes leírás

This thesis describes an in-depth study of an indolizine-based fluorophore, from understanding of its structure-photophysical property relationship to its application as a useful biological reporter. Organic fluorophores have been extensively used in the field of molecular biology owing to their excellent photophysical property, suitable cell permeability, and synthetic flexibility. Understanding of the structure-photophysical property relationship of a given fluorophore often paves the road to the development of valuable molecular probes to visualize and transcribe biological networks. In this thesis, respective chapters deal with molecular design, organic synthesis, structure-property analysis, and quantum-mechanical interpretation of unexplored family of indolizine-based molecules. This systematic exploration has led to rational development of a new microalgae lipid droplet probe, colorful bioorthogonal fluorogenic probes, and a bright mitochondrial probe, working under live cell conditions. Harnessing the optical properties of a given fluorophore has been an important topic for a couple of decades, both in industry and in academia. This thesis provides useful insights for the improvement and development of unique small fluorescent materials, or optical materials.

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Systematic Exploration of Indolizine-Based Small Fluorescent Molecules

Synthesis, Analysis and Application

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Teljes leírás

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