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Targeted Genome Editing Using Site-Specific Nucleases

Name: Targeted Genome Editing Using Site-Specific Nucleases
Brand: Springer Verlag, Japan
SKU: 9784431562351
Price: 57818 HUF
Availability: InStock

ZFNs, TALENs, and the CRISPR/Cas9 System

Szerző: Takashi Yamamoto

Nyelv:

Kötés: Puha kötésű

Kiadó: Springer Verlag, Japan

Elérhetőség: Beszállítói készleten

Küldés 8-11 napon belül

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This book serves as an introduction to targeted genome editing, beginning with the background of thi...

Információk a könyvről

Szerző

Takashi Yamamoto

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2016

oldal

205

EAN

9784431562351

ISBN

4431562354

Enbook ID

15224080

Kiadó

Springer Verlag, Japan

Súly

384

Méretek

234 x 157 x 15

Teljes leírás

This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of engineered nucleases. Applications of genome editing tools are then described in detail, in iPS cells and diverse organisms such as mice, rats, marine invertebrates, fish, frogs, and plants. Tools that are mentioned include zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9, all of which have received much attention in recent years as breakthrough technologies. Genome editing with engineered nucleases allows us to precisely change the target genome of living cells and is a powerful way to control functional genes. It is feasible in almost all organisms ranging from bacteria to plants and animals, as well as in cultured cells such as ES and iPS cells. Various genome modifications have proven successful, including gene knockout and knock-in experiments with targeting vectors and chromosomal editing. Genome editing technologies hold great promise for the future, for example in biomedical research, clinical medicine, and generation of crops and livestock with desirable traits. A wide range of readers will find this book interesting, and with its focus on applications in a variety of organisms and cells, the book will be valuable for life scientists in all fields.

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Targeted Genome Editing Using Site-Specific Nucleases

ZFNs, TALENs, and the CRISPR/Cas9 System

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