Könyv Targeted Protein Degradation Christopher Hickey

Targeted Protein Degradation

Nyelv: Angol
Kötés: Kemény kötésű
Kiadó: Springer US
Elérhetőség: Beszállítói készleten
Küldés 10-18 napon belül
76 547 Ft
This volume contains a collection of innovative techniques for studying targeted protein degradation...

Információk a könyvről

Nyelv
Angol
Kötés
Könyv - Kemény kötésű
Kiadva
2021
oldal
364
EAN
9781071616642
ISBN
1071616641
Enbook ID
35540254
Kiadó
Súly
881
Méretek
183 x 260 x 25

Teljes leírás

This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Targeted Protein Degradation: Methods and Protocols aims to ensure successful results in this emerging field of drug discovery.

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