Unidirectional, Baccal drug Delivery System using Natural Polymers

Name: Unidirectional, Baccal drug Delivery System using Natural Polymers
Brand: LAP Lambert Academic Publishing
SKU: 9783659264184
Price: 17559 HUF
Availability: InStock

Baccal drug Delivery System

Szerző: Rajesh Verma, Sundeep Chaurasia

Nyelv:

Kötés: Puha kötésű

Kiadó: LAP Lambert Academic Publishing

Elérhetőség: Kiadói készleten rendelésre

Küldés 17-27 napon belül

17 559 Ft

The oral mucosal route of drug delivery has attracted the attention worldwide for optimizing the dru...

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Szerző

Rajesh Verma, Sundeep Chaurasia

Nyelv

Angol

Kötés

Könyv - Puha kötésű

Kiadva

2012

oldal

EAN

9783659264184

Enbook ID

07138372

Kiadó

LAP Lambert Academic Publishing

Súly

147

Méretek

150 x 220 x 5

Teljes leírás

The oral mucosal route of drug delivery has attracted the attention worldwide for optimizing the drug delivery because of ease of accessibility, patient compliance and robust nature of oral mucosa. The aim of the present study was to design unidirectional, bilayered, mucoadhesive tablets for diclofenac sodium using natural polysaccharides from Tamarindus indica and Prunus amygdalus, since the natural polymers offer advantages like low cost, non toxicity and biocompatibility over synthetic polymers. The selected drug has variable bioavailability due to extensive first pass metabolism, which makes it an ideal candidate for buccal delivery. The selected hydrogels were isolated, purified and characterized for various physicochemical properties which indicated that the polymer may sustain the drug release. Further, in the formulation of mucoadhesive tablets, various process and formulation variables such as compression force, compression time, drug-polymer ratio and penetration enhancer concentration were studied and optimized on the basis of their effect on physical properties of tablets, in vitro dissolution and mucoadhesive strength.

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Unidirectional, Baccal drug Delivery System using Natural Polymers

Baccal drug Delivery System

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